Takumi has been involved in our research team since April 1997 and has been actively working on several research topics. He has devoted himself mainly for devising novel therapeutic options to treat age-related infertility, such as germinal vesicle transplantation and somatic cell haploidization. He has devised and implemented sophisticated micromanipulation and techniques to progress that are instrumental in the execution of experimental work such as nuclear transfer, piezo-ICSI, and embryo transfer in animal models as well as visualization and analysis of meiotic spindle and oocyte mitochondria. In addition, he has been playing an important role as a senior research scientist in our group to train and supervise research fellows. Furthermore, he also routinely performs embryology procedures such as ICSI (intracytoplasmic sperm injection) and genetic testing, i.e., FISH (Fluorescent in situ hybridization) analysis on gametes and embryos. In addition, he has been perfecting an assay system to identify the epigenetic influence on gametes and embryos can be evaluated. Recently, he is also working on a new research related to embryonic stem cells harvesting and dIfferentiation.